Hey Dariusz, sorry to hear you're stuck with this frustrating Anaconda Navigator issue—nothing's more annoying than waiting forever for it to load, only to get stuck on that "loading applications" screen. Since you've already tried killing related processes, let's walk through some proven fixes that should get it working smoothly again:

• 清除Navigator缓存
  Over time, cached data can pile up and bog down Navigator. Open your Anaconda Prompt (or regular terminal if you're on macOS/Linux) and run this command to reset Navigator's configuration and clear all cached files:

  anaconda-navigator --reset
  

  Once it finishes, close the terminal and launch Navigator again to see if it loads properly.

• 更新到最新版本
  Outdated versions of Navigator often have performance bugs or compatibility issues. Run this command in your terminal to update Navigator to the latest stable release:

  conda update anaconda-navigator
  

  Wait for the update to complete, then restart Navigator.

• 用安全模式排查插件问题
  Third-party plugins or misconfigured applications can cause Navigator to hang during startup. Try launching it in safe mode, which disables all non-core plugins:

  anaconda-navigator --safe-mode
  

  If Navigator loads normally in safe mode, that means one of your plugins is the culprit. You can then go into Navigator's settings and re-enable plugins one by one to find the problematic one, then disable it permanently.

• 清理conda环境冗余文件
  Cluttered conda environments with unused packages, cached installers, and broken dependencies can also slow down Navigator. Run this command to clean up all unnecessary files:

  conda clean -a
  

  This will remove unused packages, cached tarballs, and temporary files. After cleaning, run conda info to check if your environment is in a healthy state.

• 调整启动加载设置（如果能进入Navigator）
  If you manage to get Navigator open eventually, head to the Preferences menu. Look for the option labeled "Load applications on startup" and uncheck any applications you don't use regularly. This reduces the number of processes Navigator has to initialize when launching, speeding things up.

If none of these steps work, your last resort would be to reinstall Anaconda. Just make sure to back up your existing environments first using conda env export > environment.yml so you can restore them easily after reinstalling.

备注：内容来源于stack exchange，提问作者Dariusz Jot