调用infercnvpy的cnv_score函数时持续出现AttributeError: 'Series' object has no attribute 'nonzero'错误的求助

我在分析GSE214966的单细胞RNA-seq数据时，调用infercnvpy包的cnv_score()函数遇到了棘手的问题——它一直抛出AttributeError: 'Series' object has no attribute 'nonzero'错误。

我甚至尝试复现官方教程里的示例，结果还是出现完全相同的错误。这说明问题大概率出在我这边，但我翻来覆去找不到原因：已经试过重新安装所有相关包，甚至重装了Python，都没能解决问题。

错误提示说Pandas的Series对象没有nonzero属性，这确实是事实，但这是包内函数的逻辑问题，我完全不知道该从哪里入手修复。有没有大佬能帮我看看？

错误详情 #

AttributeError                            Traceback (most recent call last)
~\AppData\Local\Temp\ipykernel_9248\2255080222.py in ?()
      1 import infercnvpy as cnv
----> 2 cnv.tl.cnv_score(adata, groupby="leiden")

d:\Datos de usuario\Desktop\Single Cell Analysis\Glioblastoma (GSE214966)\Glioblastoma-GSE214966\.venv\Lib\site-packages\infercnvpy\tl\_scores.py in ?(adata, groupby, use_rep, key_added, inplace, obs_key)
     61         groupby = obs_key
     62 
     63     if groupby not in adata.obs.columns and groupby == "cnv_leiden":
     64         raise ValueError("`cnv_leiden` not found in `adata.obs`. Did you run `tl.leiden`?")
---> 65     cluster_score = {
     66         cluster: np.mean(np.abs(adata.obsm[f"X_{use_rep}"][adata.obs[groupby] == cluster, :]))
     67         for cluster in adata.obs[groupby].unique()
     68     }

d:\Datos de usuario\Desktop\Single Cell Analysis\Glioblastoma (GSE214966)\Glioblastoma-GSE214966\.venv\Lib\site-packages\scipy\sparse\_index.py in ?(self, key)
     29     def __getitem__(self, key):
---> 30         index, new_shape = self._validate_indices(key)
     31 
     32         # 1D array
     33         if len(index) == 1:

d:\Datos de usuario\Desktop\Single Cell Analysis\Glioblastoma (GSE214966)\Glioblastoma-GSE214966\.venv\Lib\site-packages\scipy\sparse\_index.py in ?(self, key)
    265                 if ix.shape != mid_shape:
    266                     raise IndexError(
    267                         f"bool index {i} has shape {mid_shape} instead of {ix.shape}"
    268                     )
---> 269                 index.extend(ix.nonzero())
    270                 array_indices.extend(range(index_ndim, tmp_ndim))
    271                 index_ndim = tmp_ndim
    272             else:  # dense array

d:\Datos de usuario\Desktop\Single Cell Analysis\Glioblastoma (GSE214966)\Glioblastoma-GSE214966\.venv\Lib\site-packages\pandas\core\generic.py in ?(self, name)
   6295             and name not in self._accessors
   6296             and self._info_axis._can_hold_identifiers_and_holds_name(name)
   6297         ):
   6298             return self[name]
-> 6299         return object.__getattribute__(self, name)

AttributeError: 'Series' object has no attribute 'nonzero'

环境信息 #

-----
anndata             0.11.3
infercnvpy          0.5.0
matplotlib          3.10.0
numpy               1.26.4
openpyxl            3.1.5
pandas              2.2.3
scanpy              1.10.4
scipy               1.15.1
session_info        1.0.0
sklearn             1.6.1
-----
PIL                 11.1.0
asttokens           NA
attr                24.3.0
attrs               24.3.0
cairo               1.27.0
cattr               NA
cattrs              NA
certifi             2024.12.14
charset_normalizer  3.4.1
colorama            0.4.6
comm                0.2.2
cycler              0.12.1
...
Python 3.12.6 (tags/v3.12.6:a4a2d2b, Sep  6 2024, 20:11:23) [MSC v.1940 64 bit (AMD64)]
Windows-10-10.0.19045-SP0
-----
Session information updated at 2025-01-16 16:27

备注：内容来源于stack exchange，提问作者Ferrixer14